Table 1 Overview of various approaches in cancer immunotherapy
From: Empowering standardization of cancer vaccines through ontology: enhanced modeling and data analysis
Antigen type | Vaccine function | Vaccine subtype | Examples |
|---|---|---|---|
Viral antigens | Preventive | Targeting Viral Infections | HPV Vaccine, Hepatitis B Vaccine |
Shared tumor antigens | Therapeutic | Shared Antigen Vaccines | Provenge (Sipuleucel-T) for prostate cancer |
Personalized tumor antigens | Therapeutic | Personalized Antigen Vaccines | NEO-PV-01 (personalized neoantigen vaccine) |
Anonymous tumor antigens | Therapeutic | In situ APC Colocalized Vaccines | IVAC MUTANOME (personalized vaccine based on tumor mutanome) |
Anonymous tumor antigens | Therapeutic | Dendritic Cell Vaccines | DCVax-L for glioblastoma |
Anonymous antigens | Therapeutic | Ex vivo Cell Vaccines | GVAX |